Example : He was keenly aware of his own shortcomings.
She pitied her sister acutely.
Acutely aware.

Synonyms : keenly

Example : An acutely debilitating virus.

Example : The road twists sharply after the light.
Turn sharp left here.
The visor was acutely peaked.
Her shoes had acutely pointed toes.

Synonyms : sharp, sharply

Example : He invested his fortune astutely.
He was acutely insightful.

Synonyms : astutely, sagaciously, sapiently, shrewdly